Endocrine Abstracts

Background: Obesity, and metabolic syndrome (MS) are highly prevalent in Saudi Arabia, increasing the risk for type 2 diabetes (T2DM), and cardiovascular disease (CVD). Oligonol produced from lychee fruit polyphenols (LFP) has been reported to reduce visceral obesity, and ameliorate MS in Japanese subject.Aim: To investigate the effect of oligonol supplementation on MS risk factors in overweight and obese Saudi females.Subjects and...

Background: Fibroblast growth factor 19 (FGF19) is an enterokine derived from the ileum, and synthesized in response to release of bile acids following food ingestion. It was proposed to be an important regulator of the postprandial adaptive metabolic response. by stimulating glycogen and protein synthesis in the liver, and down regulating glucose production after a meal. There is limited research investigating the association between FG-19 and metabolic dysregulation in overw...

Introduction: Prevalence of obesity is increasing globally and in Saudi Arabia in particular. Obesity is associated with increased risk of diabetes and cardiovascular diseases. Therefore, studies to control obesity and its effect on health are important. Chitosan has been recommended as a suitable functional supplement for controlling obesity; and consequently; its associated complications. However, results were inconclusive.Aim: To investigate the effec...